Table 1.
Group | Dieta | Ageb (days) | ALT (U/l) | AST (U/l) | Bilirubin (mg/dl) | Animals (n) |
---|---|---|---|---|---|---|
LECFH | High Cu | 84.6 ± 2 | 749.4 ± 113 | 1132 ± 124 | 27.2 ± 3 | 10 |
LECL | Low Cu | 98.7 ± 15 | 67.2 ± 5 | 157.6 ± 14 | 0.1 ± 0 | 10 |
LEA | High Cu | 125.1 ± 1 | 81.1 ± 2 | 145.9 ± 7 | 0.1 ± 0 | 10 |
LECcw8 | High Cu | 53.1 ± 1 | 100.4 ± 6 | 122.4 ± 3 | 0.1 ± 0 | 18 |
LECcw10 | High Cu | 68.6 ± 1 | 179.6 ± 43 | 157.0 ± 19 | 0.2 ± 0 | 18 |
LECcw12 | High Cu | 81.7 ± 2 | 860.1 ± 116 | 1330 ± 136 | 28.9 ± 3 | 18 |
Mean ± SE are given
aHigh- or low-copper diet was started at the age of 3 weeks
bAge at analysis
cLEC rats were individually followed up to fulminant hepatitis at week 12