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Sox21 CNEs containing lens enhancers. Schematic representation of the vertebrate Sox21 locus with coding regions in green and CNEs in blue. Two CNEs (1 and 2) are situated in an intron of the multi-exon Abcc4 gene upstream of Sox21 in all vertebrates. The co-injection assay indentified two Fugu CNEs (6 and 17), in dark blue, that upregulate GFP expression in the lens of 52 hpf old zebrafish. Tr (Takifugurubripes, Fugu).
