Figure 2.

Complex relationship between A1c and mortality in the ACCORD trial: increased mortality in the intensive-therapy group was concentrated among participants whose A1c decreased the least or did not decrease at all in the first year of intensification of glycemic therapy. The orange lines indicate the intensive treatment group with 95% confidence intervals; the blue lines indicate the standard treatment group with 95% confidence intervals

Adapted from Riddle -Diabetes Care 2010 (Fig. 2)