. 2012 Sep 20;6:15–19. doi: 10.2174/1874104501206010015

Table 1.

Inhibitory Effects of the Test Compounds on COX Enzymes and MCF-7 Cells Proliferation

MTT assay	Selectivity index^**	COX-2	COX-1	ZINC code^*	Compounds name
IC₅₀(µM)	Selectivity index^**	IC₅₀(µM)	IC₅₀(µM)	ZINC code^*	Compounds name
87.69	26.57	0.49	13.02	-	Celecoxib
178.52	11.36	0.82	9.32	01793979	Phar-095239
143	12.20	0.69	8.42	05446539	T0511-4424
97.61	20.03	0.76	15.23	05036105	Zu-4280011

This code is used to access compounds in zinc database.

^**

Selectivity index = \frac{IC50 for inhibition of COX − 1}{IC50 for inhibition of COX − 2}