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. Author manuscript; available in PMC: 2012 Oct 25.
Published in final edited form as: Psychopharmacology (Berl). 2010 Feb 3;209(1):85–94. doi: 10.1007/s00213-009-1773-3

Figure 1.

Figure 1

Effect of number of conditioning trials and length of morphine treatment on precipitated or conditioned withdrawal. Ordinates: top panels, change in body weight (g) that occurred during the 30 min session; bottom 4 rows, frequency of directly observable signs. Abscissa: PW = precipitated withdrawal (the only [Group 2] or last of 3 [Groups 1 and 3] conditioning session when naloxone [Groups 2 and 3] or saline [Group 1] was administered prior to placement in the CS environment; Conditioned Withdrawal Test Day. * = P<0.05 for paired versus unpaired groups (Groups 1 versus 2, 1 versus 3, and 4 versus 5).