Table 1.
Afferents to rostral versus caudal VTA
| Structure/Macrosystem | Subregion | CTb cells/slice |
|||
|---|---|---|---|---|---|
| Rostral VTA |
Caudal VTA |
||||
| Mean | SEM | Mean | SEM | ||
| Extended amygdala | AA | 16.6 | 3.2 | 13.3 | 2.6 |
| DBNST | 19.9* | 2.9 | 10.6 | 1.8 | |
| VBNST | 30.1* | 4.5 | 16.7 | 2.4 | |
| IPAC | 9.1* | 2.2 | 4.1 | 0.7 | |
| MeA | 7.2 | 1.2 | 6.1 | 1.1 | |
| CeA | 18.9* | 3.9 | 8.8 | 1.2 | |
| SLEA | 34.3 | 4.3 | 26.9 | 4.2 | |
| Stia | 4.2 | 1.0 | 3.0 | 0.7 | |
| Accumbens core | Core | 18.8 | 5.4 | 8.5 | 1.7 |
| Accumbens shell | Rostral Pole | 4.0 | 0.8 | 2.7 | 0.7 |
| Rostral-DM | 27.1 | 6.9 | 13.9 | 3.0 | |
| Rostral-VM | 26.8 | 5.7 | 21.4 | 6.2 | |
| Caudal-DM | 33.8 | 10.9 | 14.3 | 2.4 | |
| Caudal-VM | 47.8* | 6.5 | 29.3 | 5.7 | |
| Lateral | 16.6 | 3.5 | 18.0 | 4.4 | |
| Pallidum | VP | 61.0 | 7.7 | 48.4 | 8.1 |
| Septum | LS | 29.3 | 5.3 | 21.2 | 5.0 |
| MS | 18.4 | 5.5 | 14.2 | 4.2 | |
| Cortex-like amygdala | BLA | 1.9 | 0.4 | 1.3 | 0.3 |
| BMA | 9.1 | 1.9 | 4.9 | 1.3 | |
| Prefrontal cortex | CG1 | 3.2 | 0.8 | 2.6 | 0.6 |
| CG2 | 5.2 | 1.2 | 3.5 | 0.8 | |
| PLC | 19.9 | 2.1 | 20.6 | 5.5 | |
| ILC | 21.1 | 2.8 | 16.3 | 3.1 | |
| DP | 28.8 | 3.1 | 25.5 | 5.0 | |
| DTT | 40.1 | 10.5 | 26.0 | 4.1 | |
| NavN | 10.8 | 2.4 | 7.0 | 1.5 | |
| MOFC | 12.3 | 2.1 | 10.1 | 3.4 | |
| DLOFC | 6.8 | 2.2 | 3.5 | 1.8 | |
| LOFC | 11.4 | 2.0 | 9.5 | 2.6 | |
| VOFC | 9.5 | 1.9 | 5.3 | 1.4 | |
| DEn | 20.1 | 2.4 | 14.9 | 2.2 | |
| Claust | 13.2 | 2.4 | 9.6 | 1.4 | |
| Hypothalamus | AH | 17.5 | 3.0 | 13.4 | 3.3 |
| PH | 19.6 | 2.9 | 21.0 | 4.1 | |
| LH | 56.6 | 4.9 | 46.2 | 7.3 | |
| VMLH | 5.9 | 1.1 | 7.1 | 1.4 | |
| DMH | 31.7 | 3.8 | 28.6 | 4.6 | |
| VMH | 5.1 | 0.8 | 5.1 | 1.1 | |
| PFA | 27.0 | 3.0 | 31.1 | 5.0 | |
| LPO | 61.1 | 12.1 | 55.7 | 12.4 | |
| MPO | 51.9 | 9.3 | 42.9 | 7.8 | |
| PVH | 14.8 | 3.8 | 12.0 | 3.4 | |
| pmamm | 16.8 | 5.1 | 17.9 | 4.8 | |
| Habenula | MHb | 2.1 | 0.7 | 1.1 | 0.3 |
| LHb | 26.9 | 4.1 | 31.3 | 9.1 | |
| Raphe nucleus | Dorsal | 53.1 | 5.6 | 50.1 | 6.0 |
| Medial | 7.6 | 1.6 | 5.3 | 1.4 | |
| Paramedial | 7.7 | 1.1 | 5.7 | 0.9 | |
| PPT-Caudal | 44.2 | 5.6 | 33.2 | 4.7 | |
| RMTg/tVTA | 55.0 | 6.6 | 39.9 | 5.4 | |
| SC | 15.8 | 4.0 | 18.8 | 2.9 | |
Mean ± SEM CTb + cells per slice for forebrain and midbrain projections to rostral versus caudal VTA are shown.
*p < 0.05, stronger projection to the rostral than to the caudal VTA. All SEM values are variance values. AH, Anterior hypothalamus; BMA, basomedial amygdala; DLOFC, dorsolateral orbitofrontal cortex; LOFC, lateral orbitofrontal cortex; MHb, medial habenula, MOFC, medial orbitofrontal cortex; NavN, navicular nucleus; PVH, paraventricular hypothalamus; PH, posterior hypothalamus; pmamm, premammilary nucleus; RMTg/tVTA, rostromedial tegmental nucleus/tail of the ventral tegmental area; SC, superior colliculus; VOFC, ventral orbitofrontal cortex. Other abbreviations provided in the text.