Table 6.
Sensitivity analyses for the 50 infants with unknown HIV status
|
MTCT |
No. |
Neonatal morality |
Early mortality |
||||
|---|---|---|---|---|---|---|---|
| Mortality Rate (n) | Crude HR (95% CI) | Adjusted HR(95% CI)e | Mortality Rate (n) | Crude HR (95% CI) | Adjusted HR(95% CI)f | ||
|
Model 1a |
|
|
|
|
|
|
|
| IU |
64 |
0.050 (3) |
1.09 (0.34–3.50) |
0.97 (0.30–3.18) |
0.137 (8) |
2.26 (1.08–4.73) |
1.65 (0.77–3.50) |
| IP/ePP |
64 |
0.016 (1) |
0.35 (0.05–2.51) |
0.39 (0.05–2.85) |
0.048 (3) |
0.78 (0.25–2.50) |
1.11 (0.35–3.58) |
| NI at least for 42 days |
1004 |
0.044 (43) |
1.0 |
|
0.059 (56) |
1.0 |
|
|
Model 2b |
|
|
|
|
|
|
|
| IU |
114 |
0.268 (26) |
14.82 (8.25–26.60) |
12.03 (6.45–22.42) |
0.347 (32) |
12.65 (7.73–20.72) |
8.15 (4.83–13.74) |
| IP/ePP |
64 |
0.016 (1) |
0.73 (0.10–5.40) |
0.73 (0.10–5.47) |
0.048 (3) |
1.34 (0.41–4.39) |
1.70 (0.52–5.58) |
| NI at least for 42 days |
954 |
0.022 (20) |
1.0 |
|
0.035 (32) |
1.0 |
|
|
Model 3c |
|
|
|
|
|
|
|
| IU |
64 |
0.050 (3) |
2.28 (0.68–7.68) |
1.88 (0.55–6.43) |
0.137 (8) |
3.89 (1.79–8.44) |
2.70 (1.23–5.91) |
| IP/ePP |
114 |
0.238 (24) |
13.15 (7.25–23.84) |
11.65 (6.23–21.79) |
0.275 (27) |
9.92 (5.93–16.58) |
9.61 (5.58–16.54) |
| NI at least for 42 days |
954 |
0.022 (20) |
1.0 |
|
0.035 (32) |
1.0 |
|
|
Model 4d |
|
|
|
|
|
|
|
| IU |
67 |
0.080 (5) |
1.94 (0.77–4.93) |
1.66 (0.65–4.29) |
0.164 (10) |
2.98 (1.52–5.87) |
2.09 (1.05–4.17) |
| IP/ePP |
67 |
0.045 (3) |
1.13 (0.35–3.65) |
0.82 (0.20–3.41) |
0.076 (5) |
1.39 (0.56–3.48) |
1.55 (0.56–4.32) |
| NI at least for 42 days | 998 | 0.040 (39) | 1.0 | 0.055 (52) | 1.0 | ||
a Assume all of the 50 infants as NI at least for 42 days.
b Assume all of the 50 infants infected by IU transmission.
c Assume all of the 50 infants infected by IP/ePP transmission.
d HIV status of the 50 infants was imputed based on the predicted probability of HIV transmission.
e Adjusted for stopping breastfeeding, LBW, and preterm birth.
f Adjusted for stopping breastfeeding, LBW, and 2+ children (5–16 aged).