Table 1.
Patients with idiopathic membranous nephropathy with thromboembolic events*
| Age (y) | Sex | Year of diagnosis | Type of event, test (treatment) | Serum albumin (mg/dl), proteinuria (g/24 h) | Time to diagnosis (mth) | |
|---|---|---|---|---|---|---|
| 1 |
68 |
M |
1995 |
PE, V/Q (Pred + CycloP) |
1.8, 14 |
- 2 |
| 2 |
43 |
M |
1998 |
PE, V/Q (Pred + CycloP) |
1.7, 14 |
- 1 |
| 3 |
82 |
M |
1999 |
IleofemDVT#, US (spontaneous remission) |
2.0, 12 |
+ 6 |
| 4 |
58 |
M |
2000 |
PE, V/Q (Pred + CycloP) |
1.9, 11 |
0 |
| 5 |
58 |
F |
2001 |
RVT, US (Pred + CycloP) |
2.1, 7 |
0 |
| 6 |
68 |
F |
2002 |
PE, CTPA (Pred + CycloP) |
2.2, 5 |
0 |
| 7 |
79 |
M |
2002 |
PE#, CTPA (Pred + MMF) |
2.8, 9 |
+ 2 |
| 8 |
72 |
M |
2003 |
CVA# (Pred + MMF) |
1.7, 14 |
+ 3 |
| 9 |
50 |
M |
2003 |
DVT, US (Pred + CycloP) |
1.5, 12 |
- 2 |
| 10 |
64 |
F |
2004 |
DVT, US (Pred + CycloP) |
2.2, 5 |
- 0.5 |
| 11 |
42 |
M |
2005 |
PE, CTPA (spontaneous remission) |
2.0, 12 |
0 |
| 12 |
22 |
M |
2005 |
PE, CTPA (Pred + CsA) |
1.2, 12 |
0 |
| 13 |
39 |
M |
2005 |
PE#, CTPA (Pred + CycloP) |
1.9, 11 |
+ 1 |
| 14 | 61 | M | 2007 | PE#, CTPA (Pred + CycloP) | 1.6, 12 | + 1 |
*14/15 had complete data sets.
PE, pulmonary embolism; V/Q, ventilation/perfusion; RVT, renal vein thrombosis; CTPA, computed tomographic pulmonary angiogram; CVA, cerebrovascular accident; DVT, deep vein thrombosis; Pred, prednisolone; CsA, ciclosporin; CycloP, cyclophosphamide; MMF, mycophenolate mofetil.
All the patients who presented with TEs (patient 1, 2, 4, 5, 6, 9 – 12; 64%) were immediately anticoagulated on confirmation of the diagnosis of TE.
#Not on prophylactic anti-coagulation.