Table 2.
Somatic mutations inKRASgene
| Mutation | No. | % |
|---|---|---|
|
Codon 12 | ||
|
G12A |
13 |
9 |
|
G12C |
11 |
8 |
|
G12D* |
41 |
28 |
|
G12R |
4 |
3 |
|
G12S |
5 |
3 |
|
G12V |
32 |
22 |
|
Total |
106 |
73 |
|
Codon 13 | ||
|
E49K |
1 |
0.5 |
|
Codon 49 | ||
|
G13C |
4 |
3 |
|
G13D |
23 |
16 |
|
G13S/V |
2 |
1 |
|
Total |
29 |
20 |
|
Codon 59 | ||
|
Q61R |
2 |
1 |
|
Q61L* |
7 |
5 |
|
Total |
9 |
6 |
|
Codon 61 | ||
| A59E | 1 | 0.5 |
Percentages are referred to mutation frequencies among the 145 positive cases.
* 1 patient with two mutations.