Table 1.
Study population: age, serum lipids, biomarkers and cardiovascular risk factor distribution in cases and controls
| Cases (N = 1213) | Controls (N = 1561) | P | |
|---|---|---|---|
| Age (years) M (IQTR) |
60 (53-65) |
61 (54-66) |
0.03 |
| Sex (M/F) (N) |
852/361 |
1054/507 |
0.06 |
| SBP (mmHg) M (IQTR) |
130 (117-145) |
140 (125-155) |
<0.0001 |
| DPB (mmHg) M (IQTR) |
80 (72-86) |
82 (77-90) |
<0.0001 |
| BMI (kg/m2) M (IQTR) |
26 (23-28) |
25.1 (23-27) |
<0.0001 |
| Lipid lowering therapy N(%) |
59 (4.8) |
55 (3.6) |
0.55 |
|
Biochemistry M(IQTR) |
|
|
|
| T-Chol (mmol/L) |
6.1 (5.4-6.9) |
5.9 (5.2-6.6) |
<0.0001 |
| LDL-Chol (mmol/L) |
4.2 (3.6-4.8) |
3.9 (3.3-4.6) |
<0.0001 |
| HDL-Chol (mmol/L) |
1 (0.9-1.3) |
1.2 (1.0-1.5) |
<0.0001 |
| TG (mmol/L) |
1.7 (1.2-2.4) |
1.3 (0.9-1.8) |
<0.0001 |
| ApoA1 (g/L) |
1.3 (1.2-1.5) |
1.5 (1.3-1.7) |
<0.0001 |
| ApoB (g/L) |
1.6 (1.4-1.9) |
1.4 (1.2-1.7) |
<0.0001 |
|
Risk Factors N(%) |
|
|
|
| Family History |
400 (32) |
358 (23) |
<0.0001 |
| Hypertension |
561 (46) |
817 (53) |
0.001 |
| Diabetes |
151 (12) |
72 (4.7) |
<0.0001 |
| Hypercholesterolemia |
514 (42) |
467 (30) |
<0.0001 |
| Hypertriglyceridemia |
314 (25) |
200 (13) |
<0.0001 |
| BMI > 30 kg/m2 |
227 (19) |
197 (13) |
<0.0001 |
| Current Smokers |
580 (48) |
455 (29) |
<0.0001 |
| Physical Inactivity | 523 (43) | 536 (34) | 0.001 |
T-Chol = Total-Cholesterol; TG = Triglycerides.