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(A) Expression of cP2Y1 in the mesonephros. Ventral view of stage 20 embryo showing expression in mesonephros and limb buds. [Reproduced from Meyer et al. (1999), with permission from Wiley-Liss, Inc.] (B) Extracellular ATP is a potent mitogen for chick limb bud mesenchyme cells. Single dose of 100 µM ATP elicits a sustained increase in proliferation of bromo-2′-deoxyuridine. (Unpublished data, courtesy of Dr. M.P. Meyer.)
