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Effect of SEN1269 on 7PA2 CM-induced memory deficits (n= 14 for each study arm). (A) Effect of SEN1269 treatment on 7PA2 CM-induced lever switching errors. *P < 0.05 compared to CHO-CM, †P < 0.05 compared to 7PA2 CM. (B) Effect of SEN1269 treatment on 7PA2 CM-induced incorrect lever perseverations. **P < 0.0001 compared to CHO-CM, †P < 0.05 compared to 7PA2 CM. RS-0406 data obtained using the identical behavioural protocol included for comparison (from O'Hare et al., 2010).
