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An 18-year-old male cystic fibrosis patient, coronal T2-weighted half Fourier fast spin echo sequence (a) and coronal subtraction perfusion image (b). Notice the severe mucus plugging in the morphological T2-weighted image. The subtraction perfusion image shows correspoding areas with perfusion loss due to hypoxic vasoconstriction. Due to redistribution of perfusion both lower lobes show a high perfusion signal
