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Simulation Results of the TTP Estimates (N=50, 1000 simulation runs)
| Disease Assessment Schedule | Average Time-to-Progression Estimate in Months (% Difference from the True Median TTP) | ||
|---|---|---|---|
| Method 1 | Method 2 | Method 3 | |
| 4 weeks | 5.1 (10.9%) | 4.3 (-8.3%) | 4.6 (1.1%) |
| 6 weeks | 5.3 (15.5) | 4.0 (-12.8%) | 4.6 (0.3%) |
| 8 weeks | 5.6 (21.1%) | 3.8 (-18.0%) | 4.7 (1.2%) |
| 10 weeks | 5.8 (26.3%) | 3.5 (-23.6%) | 4.6 (0.3%) |
| 12 weeks | 6.0 (30.2%) | 3.3 (-28.5%) | 4.6 (-0.2%) |
