Table 3.
Clinical Rating Scales: Motor, ADL, Function
| N Observations | Mean | SD | |
|---|---|---|---|
| Ambulatory Capacity | 1739 | 1.7 | 1.5 |
| Schwab and England ADL | 1740 | 91.1 | 6.8 |
| UPDRS Total | 1732 | 26.2 | 11.4 |
| UPDRS Motor | 1733 | 17.8 | 8.4 |
| UPDRS ADL | 1740 | 7.2 | 4.0 |
| UPDRS Motor+ADL | 1732 | 24.9 | 11.0 |
| Total Functional Capacity (TFC) | 1739 | 12.0 | 1.4 |
| Modified Rankin Scale† | Frequency | Percent | |
| 0 (No symptoms at all) | 23 | 1% | |
| 1 (No significant disability despite symptoms) | 1344 | 77% | |
| 2 (Slight disability) | 345 | 20% | |
| 3 (Moderate disability) | 29 | 2% | |
| 4+ (Moderately severe disability/Severe disability) | 0 | 0% | |
†
During training, investigators were instructed to only consider symptoms related to PD in scoring the modified Rankin scale. All baseline data was scored in this way. In January 2012 prior to the collection of any 5-year outcome data, the administration of the modified Rankin instrument was changed to indicate that the instrument should be scored as designed, as a global score of disability.