Table 6.
| |||
---|---|---|---|
Entry | RBF3K | Isolated Yield (%) | |
1 | 12a | 93 | |
2 | 12b | 52 | |
3 | 12c | 65 | |
4 | 12d | 95 | |
5 | 12e | 96 | |
6 | 12f | 75 | |
7 | 12g | 85 | |
8 | 12h | 67 | |
9 | 12i | 61 | |
10 | 12j | 73 | |
11 | 12k | 79 | |
12 | 12l | 89 |
Reaction conditions: 1.0 equiv of trifluoroborate, 1.5 equiv of KH, 1.5 equiv of electrophile, THF, 50 °C, o/n