Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Aqueous vestibules in the closed and in the desensitized states. A, ΠNiEDDA values for the M2 residues in the closed (top) and desensitized states (bottom). The gray boxed area highlights regions of maximal change between the two states. B, ΠNiEDDA values mapped on the GLIC structure reveals differences in the solvent accessible vestibules in the two conformations. C, changes in the ΠNiEDDA moment during gating conformational change.
