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A, model of ezrin(T567D) bound to F-actin obtained using SANS data as constraint. The open structure of dezrin(T567D) is taken from Fig. 6C. B, fitting of I(Q) computed from the model shown in A to the experimental SANS I(Q) from the PIP2·dezrin(T567D)·F-actin in 0 and 10% D2O buffer. C, comparing Pc(r) value computed from the model shown in A and that from the experimental data in 0 and 20% D2O buffer. The goodness of fit value of χ2 is shown on the graph.
