TABLE 1.

Selected cell-cell interaction and other lung genes regulated by Grhl2 in MLE15 cells

(p < 0.02; FDR adjusted p value <0.3, fold-change >1.25.

Symbol	Description	-Fold change	p value	FDR	Lung expression E14.5	Probeset
Fabp5	Fatty acid-binding protein 5	−3.1	0.0014	0.19		10585699
Fgb	Fibrinogen β chain	−2.6	0.0058	0.23		10498981
Hapln1	Hyaluronan and proteoglycan link protein 1	−2.3	0.0003	0.17		10406519
Klf12	Kruppel-like factor 12	−2.1	0.0083	0.25		10422013
Cldn8	Claudin 8	−1.9	0.0061	0.24	E +	10440647
Sema3a	Semaphorin 3A	−1.5	0.0003	0.17		10519717
Sema3c	Semaphorin 3C	−1.4	0.0051	0.23	E + + +	10519886
Cldn4	Claudin 4	−1.3	0.0471	0.39	E + + +	10534395
Efna5	Ephrin A5	−1.3	0.0008	0.17		10452419
Sema6d	Semaphorin 6D	−1.3	0.0033	0.21		10475544
Notch1	Notch gene homolog 1	−1.3	0.0124	0.27	E + + +	10481056
Sftpd	Surfactant associated protein D	−1.3	0.0114	0.27	E +	10419096
Nrp2	Neuropilin 2	−1.2	0.0064	0.24	E +	10346843
Efna1	Ephrin A1	−1.2	0.0035	0.22	E + + +	10499536
Plxnb1	Plexin B1	−1.2	0.0011	0.19	E + + +	10589368
Plxna2	Plexin A2	−1.2	0.0002	0.15		10352867
Grhl2	Grainyhead-like 2	−1.2	0.0602	0.42	E + + +	10423770
Ephb3	Eph receptor B3	−1.2	0.0060	0.24		10434559
Notch2	Notch gene homolog 2	−1.2	0.0053	0.23		10494595
Plxna4	Plexin A4	−1.2	0.0047	0.23		10543802
Plxna1	Plexin A1	−1.2	0.0113	0.27		10546184
Enpp2	Ectonucleotide pyrophosphatase/phosphodiesterase 2	2.2	0.0066	0.24		10428619
Scgb3a1	Secretoglobin, family 3A, member 1	2.4	0.0018	0.19	E + +	10375608
Hddc2	HD domain containing 2	2.5	0.0054	0.23		10362394
Bex1	Brain expressed gene 1	2.9	0.0005	0.17		10606868