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. 2012 Sep 7;287(44):37434–37446. doi: 10.1074/jbc.M112.406090

TABLE 1.

Affinities for human and mouse BCMA as measured by BIAcore

Values represent the average of a global fit using three curves from separate experiments. Ru, resonance units.

Protein ka kd KD
m1 s1 s1 m
Affinities for human BCMA-Fc
    WT 5.3 ± 0.1 × 105 2.0 ± 0.1 × 10−4 3.8 ± 0.1 × 10−10
    R206E 3.3 ± 0.0 × 105 1.5 ± 0.0 × 10−4 4.6 ± 0.0 × 10−10

Affinities for mouse BCMA-Fc
    WT 8.9 ± 0.0 × 105 1.3 ± 0.0 × 10−4 1.4 ± 0.1 × 10−10
    R206E 16 ± 0.0 × 105 1.5 ± 0.0 × 10−4 0.95 ± 0.3 × 10−10