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. 2012 Oct 5;53(6):1147–1153. doi: 10.3349/ymj.2012.53.6.1147

Fig. 4.

Fig. 4

A representative case of good response in mouse #2. (A) Serial DCE-MRI with color mapping shows higher pretreatment Ktrans (0.29) and marked reduction in Ktrans after the first radiation therapy (K1R=0.47). (B) H&E staining of the corresponding section in mouse #2. The original magnification is ×2. Necrosis is identified in the center of the tumor. The red line indicates the tumor border and the blue line indicates the area of necrosis. The necrosis factor was 0.46. Histogram shows the heterogeneous distribution of Ktrans at baseline with an SD of 0.09 (C) and the homogenous distribution of Ktrans with an SD of 0.05 after the first radiation therapy (D). DCE-MRI, dynamic contrast-enhanced magnetic resonance imaging; SD, standard deviation; H&E, hematoxylin and eosin.