Table 3.
Gene | Module gene set$ | # SNPs | Chr. | Start (bp) | Stop (bp) | PVEGAS-all | PVEGAS-top | PminP |
---|---|---|---|---|---|---|---|---|
NOS1AP | a, m | 125 | 1 | 160306204 | 160606437 | 0.005 | 0.007 | 1.07 × 10-4 |
PTGS2 | t, m | 14 | 1 | 184907591 | 184916179 | 0.013 | 8.5 × 10-4 | 1.07 × 10-5 |
TSNAX | t | 11 | 1 | 229731021 | 229768892 | 0.476 | 0.306 | 0.113 |
DISC1 | m | 106 | 1 | 229829183 | 230243641 | 0.349 | 0.100 | 0.004 |
FLNB | a | 47 | 3 | 57969166 | 58133017 | 0.030 | 0.034 | 0.007 |
GSK3B | t | 40 | 3 | 121028235 | 121295203 | 0.141 | 0.073 | 0.011 |
PDE4D | m | 193 | 5 | 58300622 | 59225378 | 0.277 | 0.018 | 6.16 × 10-5 |
IL4 | a | 12 | 5 | 132037271 | 132046267 | 0.069 | 0.019 | 0.007 |
DTNBP1 | a | 52 | 6 | 15631017 | 15771250 | 0.020 | 0.022 | 0.008 |
RPP21 | t, m | 48 | 6 | 30420915 | 30422611 | 0.014 | 0.001 | 1.04 × 10-4 |
LTA | m | 43 | 6 | 31648071 | 31650077 | 0.450 | 0.075 | 0.003 |
TNF | m | 43 | 6 | 31651328 | 31654091 | 0.598 | 0.184 | 0.003 |
ESR1 | a, t, m | 86 | 6 | 152053323 | 152466101 | 0.091 | 0.027 | 0.004 |
TBP | t | 13 | 6 | 170705395 | 170723872 | 0.031 | 0.019 | 0.010 |
EGFR | t, m | 72 | 7 | 55054218 | 55242525 | 0.556 | 0.294 | 0.026 |
YWHAZ | a, t, m | 17 | 8 | 102000089 | 102034745 | 0.857 | 0.685 | 0.268 |
GRIN1 | a, t, m | 3 | 9 | 139153429 | 139183029 | 0.016 | 0.005 | 0.004 |
ATE1 | m | 59 | 10 | 123492614 | 123677536 | 0.491 | 0.155 | 9.28 × 10-4 |
IFNG | t, m | 26 | 12 | 66834816 | 66839788 | 0.068 | 0.007 | 0.002 |
NOS1 | m | 45 | 12 | 116135361 | 116283965 | 0.643 | 0.315 | 0.028 |
DGKH | t | 68 | 13 | 41520888 | 41701888 | 0.106 | 0.031 | 0.002 |
AKT1 | a, t | 6 | 14 | 104306731 | 104333125 | 0.076 | 0.056 | 0.026 |
TP53 | t, m | 11 | 17 | 7512444 | 7531588 | 0.540 | 0.219 | 0.075 |
PRKCA | t | 129 | 17 | 61729387 | 62237324 | 0.995 | 0.857 | 0.029 |
MAG | m | 13 | 19 | 40474877 | 40496547 | 0.097 | 0.037 | 0.003 |
DNMT3B | t, m | 21 | 20 | 30813851 | 30860823 | 0.026 | 0.002 | 1.75 × 10-4 |
MYH9 | m | 37 | 22 | 35007271 | 35113927 | 0.050 | 0.017 | 5.75 × 10-4 |
$a: VEGAS-all; t: VEGAS-top; m: minP.