Table 3.

P53 overlapping cluster membership

Pathway Name, (enrichment p-value)	de novo Gene Membership	de novo Gene Ontology	de novo Protein Interactants	Weighted Consolidation	Enrichment Consolidation
Direct p53 effectors, (p = 1.16 × 10-9)	■	■	■	■	■
p53 pathway, (p = 6.19 × 10-9)	■	■	■	■	■
p53 signaling pathway, (p = 9.84 × 10-7)	▲	■	■	▲	■
p53-dependent G1 DNAdamage response, (p = 0.15)	●	●	■	▼	n/a
p53-dependent G1/S DNA damage checkpoint, (p = 0.15)	●	●	■	▼	n/a
p53-independent DNA damage response, (p = 0.25)	●	●	■	●	n/a
p53-independent G1/S DNA damage checkpoint, (p = 0.25)	●	●	■	●	n/a

Note: matching symbols in a column indicate shared cluster membership. n/a indicates non-enriched pathway not included in any cluster. Dividers and matching symbols indicate pathways groups within a consolidation method.