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. 2012 Oct 26;13(Suppl 6):S18. doi: 10.1186/1471-2164-13-S6-S18

Table 4.

RNAi resultant gene set overlapping cluster membership

Pathway Name, (enrichment p-value) de novo Gene Membership de novo Gene Ontology de novo Protein Interactants Weighted Consolidation Enrichment Consolidation
Base excision repair (p = 0.58) n/a
Mismatch Repair (p = 0.75) n/a

Homologous Recombination Repair (p = 0.73) n/a
DNA damage response (p = 0.09) n/a

Nucleotide Excision Repair (p = 1.99 × 10-4)
Proteasome (p = 3.4 × 10-3)
Basal Transcription (p = 2.97 × 10-11)
Ribosome (p = 6.65 × 10-3)

TOR pathway (p = 2.90 × 10-3)
Notch Signaling Pathway (p = 3.05 × 10-4)

Glutathione Biosynthesis (p = 0.11) n/a

Note: RecQ helicases and ATPase were not found among the human pathways. p-values are derived from one-tail Fisher's Exact test, before multiple test correction. Dividers and matching symbols indicate pathways groups within a consolidation method.