Figure 2.

Distribution of the occurrence frequency of TCF-1, Ets-1 and E2F in human promoter database (EPD) in the proximal promoter region. The individual occurrence frequency distributions of the various transcription factors in human promoters from EPD. The y-axis is the OF of the transcription factors TCF-1 (A), Ets-1 (B) and E2F (C) motifs. The x-axis shows the areas upstream and downstream of the TSS which is at 0. The blue horizontal line shows the expected occurrence frequency OF_r for each of the factors calculated from the shuffled sequence dataset.