Table 3.

Clinical variables in patients with non-group A (C and G) and Group A compared with patients having no growth of C,G or A streptococci

	Patients with group A, C or G streptococci (%)	Patients with no group A, C or G streptococci (%)	Univariate OR (95% CI)	P-value	aMultivariate OR (95% CI)	P-value
Prior duration ≤3 days	123/180 (68)	184/409 (45)	2.64 (1.82 to 3.82)	<0.001	1.92 (1.26 to 2.92)	0.002
Cervical glands	163/178 (92)	290/404 (72)	4.27 (2.41 to 7.57)	<0.001	2.93 (1.55 to 5.52)	0.001
Severely inflamed tonsils	56/177 (32)	45/397 (11)	3.62 (2.32 to 5.64)	<0.001	2.28 (1.39 to 3.74)	0.001
Absence of runny nose	130/180 (72)	223/409 (55)	2.17 (1.48 to 3.17)	<0.001	1.55 (0.99 to 2.41)	0.054
Age group ≤10 years	32/181 (18)	32/410 (8)	2.54 (1.50 to 4.29)	0.001	1.95 (1.05 to 3.62)	0.033
Sore throat (moderately bad or worse)	175/181 (97)	358/409 (88)	4.16 (1.75 to 9.87)	0.001	3.31 (1.24 to 8.83)	0.017
Absence moderately bad cough	159/181 (88)	268/410 (65)	3.83 (2.35 to 6.25)	<0.001	2.73 (1.56 to 4.76)	<0.001
Purulent tonsils	95/180 (53)	126/409 (31)	2.51 (1.75 to 3.60)	<0.001	1.06 (0.67 to 1.66)	0.814
Fever (during last 24 hours)	143/181 (79)	235/410 (57)	2.80 (1.86 to 4.21)	<0.001	1.69 (1.05 to 2.71)	0.030
Muscle aches moderately bad	70/180 (39)	98/409 (24)	2.02 (1.39 to 2.94)	<0.001	2.20 (1.41 to 3.42)	<0.001
Headache	135/181 (75)	243/409 (59)	2.00 (1.36 to 2.96)	<0.001	1.41 (0.89 to 2.25)	0.143

^aAll multivariate estimates adjusted for prior duration, cervical glands, severity of sore throat, severity of inflammation, the absence of cough, the absence of coryza, muscle aches and fever. If other streptococci are included (band D) then the significant predictors are short prior duration, cervical glands, severity of sore throat, severity of inflammation, absence of cough, absence of coryza, and muscle aches.