Table 2. Cytotoxic Activities of 1–5 against HepG2 Cells and Antibiotic Activities of 1–5 against P. berghei, E. coli, B. subtilis, C. albicans, and S. cerevisiaea.
| HepG2 | P. berghei | E. coli | B. subtilis | C. albicans | S. cerevisiae | |
|---|---|---|---|---|---|---|
| compound | IC50 (μM) | IC50 (μM) | MIC (μg/mL) | MIC (μg/mL) | MIC (μg/mL) | MIC (μg/mL) |
| 1 | >100 | 38 | >50 | >50 | >50 | >50 |
| 2 | >100 | 50 | >50 | >50 | >50 | >50 |
| 3 | >100 | >100 | >50 | >50 | >50 | >50 |
| 4 | >100 | 18.5 | >50 | 25 | >50 | >50 |
| 5 | 36.1 | 3.0 | >50 | 3.13 | >50 | >50 |
a
Data represent the average of two experiments each performed in triplicate. The MIC is defined as the lowest concentration that gave less than 5% of the maximum growth.