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. 2012 Jul 18;9(77):3469–3479. doi: 10.1098/rsif.2012.0428

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Figure 7. — (a) Representative brightfield and fluorescent image (bottom-up view) of a cell before shear deformation, with nuclei (blue) and actin (red) shown at a focal plane near the base. (b) Predicted distribution of the actin cytoskeleton before shear deformation for the active model (E_cyto = 1.5 kPa, T_max = 0.85 kPa, ). (c) Representative brightfield and fluorescent image (bottom-up view) of a cell after shear deformation. (d) Predicted distribution of the actin cytoskeleton following 10.9 µm of probe indentation. The arrow indicates the direction of probe movement.

Inline graphic — (a) Representative brightfield and fluorescent image (bottom-up view) of a cell before shear deformation, with nuclei (blue) and actin (red) shown at a focal plane near the base. (b) Predicted distribution of the actin cytoskeleton before shear deformation for the active model (E_cyto = 1.5 kPa, T_max = 0.85 kPa, ). (c) Representative brightfield and fluorescent image (bottom-up view) of a cell after shear deformation. (d) Predicted distribution of the actin cytoskeleton following 10.9 µm of probe indentation. The arrow indicates the direction of probe movement.