Figure 3.  .

The role of IL-1R1 in S. marcescens–induced corneal inflammation and infection. Corneas of C57BL/6 and IL-1R1^−/− mice were abraded and infected with S. marcescens as before. IL-1α and CXCL1/KC production was assessed after 3 and 24 hours (A, B). Data are mean ± SD of three replicate values. Stromal thickness, haze, and bacterial survival (CFU) were examined at 24 hours post infection (C, D). Data points represent individual corneas, and all data are representative of three repeat experiments.