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The role of TLR4 and TLR5 in S. marcescens–induced corneal inflammation and infection. Corneas of C57BL/6, TLR4−/−, TLR5−/−, and TLR4/5−/− mice were abraded and infected with live S. marcescens as before. After 24 and 48 hours, stromal thickness and haze, and bacterial survival (CFU) were assessed. Data points represent individual corneas. This experiment was repeated twice with similar results.
