Table 4:
Independent Associations between serum aminotransferase levels and hyperlipidemia, DM and, NAFLD
| Aminotransferase Level | Number | Odds Ratio (95% CI) for DM | Odds Ratio (95% CI) for NAFLD | Odds Ratio (95% CI) for Hyperlipemia | |||
|---|---|---|---|---|---|---|---|
|
| |||||||
| DM n (%) | Multivariate Adjusted* | NAFLD n (%) | Multivariate Adjusted* | Hyperlipemia, n(%) | Multivariate Adjusted* | ||
| Men | |||||||
| ALT<20 (IU/L) | 812 | 29(3.57) | 1 | 50(6.16) | 1 | 259(31.90) | 1 |
| 20–29 | 453 | 32(7.06) | 1.69(0.99–2.89) | 54(11.92) | 1.35(0.87–2.09) | 209(46.14) | 1.35(1.15–1.74) |
| 30–39 | 238 | 16(6.72) | 1.44(0.75–2.79) | 34(14.29) | 1.50(1.29–2.51) | 137(57.56) | 1.92(1.39–2.64) |
| 40–49 | 108 | 8(7.41) | 1.41(0.60–3.31) | 34(31.48) | 3.26(1.84–5.77) | 72(66.67) | 2.53(1.59–4.02) |
| >50 | 150 | 17(11.33) | 2.29(1.16–4.54) | 51(34.00) | 3.66(2.19–6.11) | 113(75.33) | 3.44(2.24–5.29) |
| Total | 1761 | 102(5.79) | 223(12.66) | 790(44.86) | |||
| Women | |||||||
| ALT<20 (IU/L) | 1460 | 51(3.49) | 1 | 194(13.29) | 1 | 655(44.86) | 1 |
| 20–29 | 373 | 20(5.36) | 1.36(1.19–2.34) | 100(26.81) | 1.58(1.13–2.21) | 210(56.30) | 1.24(0.97–1.59) |
| 30–39 | 108 | 5(4.63) | 1.28(1.16–2.85) | 45(41.67) | 1.89(1.11–3.20) | 62(57.41) | 0.94(0.61–1.45) |
| 40–49 | 66 | 10(15.15) | 3.86(1.81–8.26) | 31(46.97) | 2.44(1.30–4.58) | 44(66.67) | 1.37(0.792.39) |
| >50 | 67 | 8(11.94) | 2.72(1.17–6.33) | 32(47.76) | 3.23(1.70–6.14) | 46(68.66) | 1.70(0.97–2.99) |
| Total | 2074 | 94(4.53) | 402(19.38) | 1017(49.04) | |||
*
Adjusted for age, BMI, occupation, cultural and educational level, income level, smoking, alcohol intake, and waist circumference. ALT, alanine aminotransferase; AST, aspartate aminotransferase; DM, diabetes mellitus; NAFLD, non-alcoholic fatty liver disease; BMI, body mass index. The Odds Ratio between AST and metabolic disorders was not shown because the associations in the results were weaker, especially after multivariate adjustment