Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Amination of OctylB(pin).a
| |||
|---|---|---|---|
| entry | CH3ONH2 (equiv) | base (equiv) | yield (%) |
| 1 | 1.0 | n-BuLi (1.0) | 41 |
| 2 | 2.0 | n-BuLi (2.0) | 72 |
| 3 | 3.0 | n-BuLi (3.0) | 84 |
| 4 | 3.0 | MeLi (3.0) | 48 |
| 5 | 3.0 | NaH (3.0) | <5 |
| 6 | 3.0 | KH (3.0) | <5 |
| 7 | 3.0 | K(OtBu) (3.0) | 16 |
| 8 | 3.0 | Li(OtBu) (3.0) | <5 |
Reactions were conducted as described in the text. The percent value given refers to the isolated yield of purified material and is an average of two experiments.
