TABLE 2—
Multivariable Models Predicting Stage II Versus Stage I and Stage III/IV Versus Stage I Among Cervical Cancer Patients: National Cancer Database, United States, 2000–2007
Variable | Stage II vs Stage I, RR (95% CI) | Stage III/IV vs Stage I, RR (95% CI) |
Age, y | ||
21–34 (Ref) | 1.00 | 1.00 |
35–39 | 1.22 (1.15, 1.29) | 1.25 (1.18, 1.32) |
40–44 | 1.44 (1.36, 1.52) | 1.50 (1.43, 1.58) |
45–49 | 1.72 (1.63, 1.82) | 1.83 (1.74, 1.92) |
50–54 | 1.92 (1.82, 2.03) | 2.20 (2.09, 2.31) |
55–59 | 1.98 (1.87, 2.10) | 2.32 (2.21, 2.43) |
60–64 | 1.98 (1.86, 2.11) | 2.31 (2.20, 2.43) |
65–69 | 1.98 (1.85, 2.13) | 2.24 (2.11, 2.38) |
70–85 | 2.19 (2.05, 2.35) | 2.49 (2.35, 2.63) |
Insurance status | ||
Private (Ref) | 1.00 | 1.00 |
Uninsured | 1.43 (1.38, 1.49) | 1.44 (1.40, 1.49) |
Medicaid | 1.32 (1.28, 1.37) | 1.37 (1.34, 1.41) |
Younger Medicarea | 1.13 (1.05, 1.21) | 1.12 (1.06, 1.19) |
Older Medicareb | 1.19 (1.12, 1.26) | 1.20 (1.15, 1.26) |
Missing | 1.17 (1.10, 1.25) | 1.27 (1.21, 1.33) |
Race/ethnicity | ||
Non-Hispanic White (Ref) | 1.00 | 1.00 |
Hispanic | 1.05 (1.01, 1.09) | 0.86 (0.83, 0.89) |
African American | 1.05 (1.02, 1.09) | 1.05 (1.02, 1.08) |
Other/Asian | 1.06 (1.01, 1.12) | 0.88 (0.84, 0.92) |
Missing | 1.01 (0.97, 1.06) | 0.96 (0.93, 1.00) |
Histology | ||
SCC (Ref) | 1.00 | 1.00 |
Adenocarcinoma | 0.71 (0.68, 0.73) | 0.69 (0.67, 0.71) |
Adenosquamous/GC | 0.88 (0.83, 0.94) | 0.90 (0.86, 0.96) |
Other specified carcinoma | 1.00 (0.90, 1.12) | 1.29 (1.24, 1.35) |
Unspecified carcinoma | 0.91 (0.84, 0.99) | 1.23 (1.18, 1.28) |
Diagnosis year | ||
2000–2001 (Ref) | 1.00 | 1.00 |
2002–2003 | 1.04 (1.01, 1.08) | 1.07 (1.04, 1.09) |
2004–2005 | 1.06 (1.03, 1.10) | 1.10 (1.07, 1.13) |
2006–2007 | 1.06 (1.02, 1.09) | 1.13 (1.10, 1.16) |
Note. CI = confidence interval; GC = glassy cell carcinoma; RR = risk ratio; SCC = squamous cell carcinoma. Model also adjusted for area-level education, geographic region, and urban or rural residence.
Aged 18–64 years.
Aged ≥ 65 years.