Table 2.
Immunological findings and serum cytokine levels
| Parameters | Values | Normal ranges |
|---|---|---|
| IgG | 1,072 mg/dl | 870–1,700 |
| IgA | 150 mg/dl | 110–410 |
| IgM | 414 mg/dl | 46–260 |
| IgE | 22 U/ml | <216 |
| IgD | 2 mg/dl | 2–12 |
| IgG4 | 16.6 mg/dl | 4.8–150 |
| M-protein | Negative | Negative |
| ASO | <20 U/ml | <187 |
| ASK | ×80 | ×1,280 |
| Rheumatoid factor | ×160 | ×40 |
| Anti-nuclear antibody | Negative | Negative |
| Anti-ds DNA antibody | Negative | Negative |
| Anti-Sm antibody | Negative | Negative |
| Anti-cardiolipin antibody (IgM-class) | Negative | Negative |
| Anti-cardiolipin antibody (IgG-class) | Negative | Negative |
| Anti-SS-A antibody | Negative | Negative |
| Anti-SS-B antibody | Negative | Negative |
| Anti-GBM antibody | Negative | Negative |
| Cryoglobulin (IgG-class) | Positive | Negative |
| Cryocrit | <1% | 0 |
| MPO-ANCA | <1.3 U/ml | <9.0 |
| PR3-ANCA | 44.1 U/ml | <3.5 |
| Immune complex | 29.5 μg/ml | <2.9 |
| C3 | 19 mg/dl | 86–160 |
| C4 | 10 mg/dl | 17–45 |
| CH50 | <11.0 U/ml | 24.7–39.5 |
| Hepatitis B antigen | Negative | Negative |
| Hepatitis C antibody | Negative | Negative |
| Serological tests for syphilis | Negative | Negative |
| HIV antibody | Negative | Negative |
| Blood culture | Negative | Negative |
| QuantiFERON-TB test | Negative | Negative |
| TNF-α | 21.2 pg/ml | 0.6–2.8 |
| IL-1β | 15 pg/ml | <10 |
| IL-6 | 97.6 pg/ml | <0.4 |