Figure 3. Effects of mitoTEMPO on MAP and heart rate.
A, ICV mitoTEMPO significantly attenuated MAP in Ang II-induced hypertension in a dose dependent manner (100 and 170ng/kg/min). B, Neither does of SC mitoTEMPO did not attenuate MAP. C, Heart rate did not show differences between mitoTEMPO treatment groups but Ang II infusion group. Bar graph is mean±SEM. *P<0.05, **P<0.01 vs control. N=7–8