Figure 4. Effects of ICV mitoTEMPO on activated microglia in the PVN.
A, Ang II-induced Iba-1 positive activated microglia within PVN were reduced to control level by ICV mitoTEMPO treatment. B, Quantification of the number of Iba-1 positive microglia in the PVN. C, mRNA of CD11b, a marker of activated microglia. D, mRNA of IL1β. E, mRNA of TNFα. *P<0.05 vs control, #P<0.05 vs Ang II. Scale bars=10μm