PLA2G12A
|
1
|
Participates in helper T cell Immune response [16]
|
Association with AMD [33]
|
IL-23R
|
11
|
Regulates IL-1A expression [35]
|
Regulator of IL-17 expression [35]
|
STAT3
|
1
|
Transcriptional factor in IL-23/IL-17 pathway [35]
|
Regulator of IL-17 Expression [35]
|
VEGFA
|
4
|
Promotes Neovascularization [36]
|
Higher secretion in AMD patients [37]
|
KDR
|
1
|
Receptor for VEGFA [38]
|
Differences in receptor expression or function may affect VEGF binding [39]
|
HIF-1A |
3 |
Oxygen dependent transcriptional activator [40] |
Regulates VEGF expression [40] |