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. 2012 Oct 26;7(10):e48133. doi: 10.1371/journal.pone.0048133

Table 4. Proteins identified to be significantly differentially regulated by mass spectrometry following 2D gel electrophoresis.

Direction FeD to control Protein Function
Up Alpha-enolase Glycolysis; Cell proliferation
Trypsin I precursor Digestion
Carbonyl reductase Reduction catalyst
ADP-ribosylation factor-like 3 Cell proliferation; Cytoskeletal remodelling; Protein trafficking
Fructose-biphosphate aldolase A Glycolysis, gluconeogenesis
Farnesyl-pyrophosphate synthetase Steroid/lipid synthesis
SUG1 26S Proteasome subunit
Down ?ihydropyrimidinase-related protein 2 Cytoskeletal remodelling
Chaperonin containing TCP1, subunit 5 (Epsilon) Protein folding; Cytoskeletal remodelling
Valosin-containing protein Export of misfolded proteins
Alpha-enolase Glycolysis; Cell proliferation
Phosphopyruvate hydratase Glycolysis, gluconeogenesis
Nucleophosmin Protein chaperone; Cell proliferation
Proteasome subunit alpha type 3-like Proteasome complex
Prohibitin Protein chaperone; Cell proliferation
Dihydrofolate reductase Folate metabolism; Cell proliferation
Transthyretin precursor Thyroxine and retinol transport
Dihydrolipoamide S-acetyltransferase Pyruvate dehydrogenase complex