Figure 3. Beam-walking and corner testing in middle-aged DCX-TK⁽⁻⁾ and DCX-TK⁽⁺⁾ mice after dMCAO.

Middle-aged DCX-TK⁽⁻⁾ and DCX-TK⁽⁺⁾ mice underwent dMCAO after treated with vehicle or GCV for 14 days, then behavioral tests were conducted at intervals over the next 12 wks (weeks). (A) Forelimb slip steps of Beam-walking test (higher scores correspond to more severe deficits). (B) Hindlimb slip steps of Beam-walking test (higher scores correspond to more severe deficits). (C) Scores of corner test (higher scores correspond to more severe deficits). *P<0.05.