Figure 4. EBST, limb-placing and rotarod testing in middle-aged DCX-TK⁽⁻⁾ and DCX-TK⁽⁺⁾ mice after dMCAO.

Middle-aged DCX-TK⁽⁻⁾ and DCX-TK⁽⁺⁾ mice underwent dMCAO after treated with vehicle or GCV for 14 days, then behavioral tests were conducted at intervals over the next 12 wks. (A) Scores of elevated body swing test (EBST; lower scores correspond to more severe deficits). (B) Scores of limb-placing test (lower scores represent more severe deficits). (C) Scores of rotarod test (lower scores represent more severe deficits). *P<0.05.