Table 1. Demographics, Disease Characteristics, and Adipokine Serum Concentrations of Study Participants Categorized by Gender.
| Female | Male | |
| N = 39 | N = 5 | |
| Mean ± SD or N (%) | ||
| Age | 63.5±8.3 | 72.6±8.4 |
| Age | ||
| 45–50 | 2 (5.1) | 0 |
| 51–60 | 11 (28.2) | 0 |
| 61–70 | 14 (35.9) | 2 (40.0) |
| 71–80 | 12 (30.8%) | 2 (40.0) |
| 80+ | 0 | 1 (20.0) |
| BMI (kg/m2) | 30.0±7.3 | 29.5±4.7 |
| BMI status | ||
| Normal (BMI<25) | 9 (23.1) | 0 |
| Overweight (25≤BMI<30) | 11 (28.2) | 4 (80.0) |
| Obese (BMI≥30) | 19 (48.7) | 1 (20.0) |
| Race/ethnicity | ||
| Non-Hispanic White | 34 (87.2) | 5 (100.0) |
| Non-Hispanic Black | 1 (2.6) | |
| Hispanic | 3 (7.7) | |
| Other | 1 (2.6) | |
| Osteoarthritis family history | 30 (76.9) | 4 (80.0) |
| Polyarticular osteoarthritis | 33 (84.6) | 3 (60.0) |
| Current smoking | 4.0 (10.3) | 0.0 (100.0) |
| History of Coronary Artery Disease | 1 (2.3) | 0 |
| History of Thyroid Disease | 14 (31.8) | 0 |
| Diabetes Mellitus | 8 (18.2) | 0 |
| NSAIDs | 7 (18) | 1 (20) |
| Osteoarthritis disease duration (years) | 8.9±6.7 | 8.6±4.4 |
| Leptin (ng/mL) | 32.2±23.5 | 18.5±13.4 |
| Adiponectin high MW (ug/mL) | 4.8±2.9 | 2.5±2.2 |
| Adiponectin mid MW (ug/mL) | 1.4±0.5 | 1.0±0.2 |
| Adiponectin total (ug/mL) | 7.9±3.6 | 5.3±1.0 |
| Resistin (ng/mL) | 7.3±3.5 | 9.4±1.5 |
| Hand x ray Kallman scores | 43.3±17.4 | 46.2±10.8 |
| Pain (VAS 0–100 mm)* | 47.7±23.7 | 66.0±8.9 |
| Leptin/Adiponectin total ratio (10−3) | 4.9±3.7 | 3.6±2.7 |
Notes: BMI, body mass index. MW, molecular weight.
*
Data summarized from participants who entered secondary analysis of adipokines and pain (35 women and 5 men).