Table 1.
Demographic characteristics, cardiovascular risk factors, medications, and previous thrombotic and obstetrical events at baseline.
| aPL request N=208 |
CBC request N=208 |
Total | |
|---|---|---|---|
| Age in years, mean (SD) | 46.3 (14.2) | 46.6(14.2) | 46.5 (14.2) |
| Education in years, mean (SD)* | 12.7 (2.5) | 13.0 (2.8) | 12.9 (2.7) |
| Gender, % female | 173 (83.2) | 173 (83.2) | 346 (83.2) |
| Race, % Caucasian | 178 (85.6) | 172 (82.7) | 350 (84.1) |
| Smoking (%) | 59 (28.4) | 56 (26.9) | 115(27.6) |
| HBP (%)† | 34(16.4) | 33(15.9) | 67(16.1) |
| DM (%)† | 9 (4.3) | 14(6.7) | 23 (5.5) |
| SLE (%)† | 82 (39.4) | 3(1.4) | 85 (20.4) |
| FMH (%)† | 109(52.4) | 92 (44.2) | 201 (48.3) |
| Prednisone (%) | 35(16.8) | 1 (0.5) | 36 (8.7) |
| Hydroxychloroquine (%) | 52 (25.0) | 2(1.0) | 54(13.0 |
| Acetylsalicylic acid (%) | 46 (28.9) | 15(13.5) | 61 (21.2) |
| Warfarin (%) | 28(13.5) | 4(1.9) | 32 (7.7) |
| Estrogen (%)* | 25 (14.5) | 37(21.4) | 62(17.9) |
| Confirmed thrombotic events (%)§ | 57 (27.4) | 12(5.8) | 69 (16.6) |
| Thrombotic events >1 (%)§ | 25 (12.0) | 2(1.0) | 27 (6.5) |
| Reported miscarriages (%)* | 0 (0.0) | 1 (0.5) | 1 (0.2) |
| Reported fetal loss (%)*§ | 30 (17.3) | 12 (6.9) | 42 (12.1) |
| Reported premature births (%)* | 13 (7.5) | 9 (5.2) | 22 (6.4) |
*
For education, N = 201 and 206 for the aPL request and CBC request groups, respectively; for estrogen and obstetrical events, N = 173 each for the aPL request and CBC request females, respectively.
†
HBP = high blood pressure; DM = diabetes mellitus; SLE = systemic lupus erythematosus; FMH = family history for CVD.
§
Risk difference (95% CI) = 21.6% (14.8% to 28.5%) for confirmed thrombotic events > 1; 11.1 % (6.4% to 15.7 %) for thrombotic events > 1; and 10.4% (3.6% to 17.2%) for reported fetal loss.