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Representative immunoblots for (A) angiostatin, (B) endostatin, and (C) tumstatin after MMP-9 inhibition. As indicated by the bar graphs, there was a significant down-regulation of angiostatin (*p = 0.04), endostatin (*p = 0.002), and tumstatin (*p = 0.05) in hypertrophied hearts receiving an MMP-9 inhibitor. Equal protein loading was confirmed by staining of gels with Coomassie brilliant blue.
