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. Author manuscript; available in PMC: 2013 Oct 4.
Published in final edited form as: Oncogene. 2012 Jul 23;32(14):1772–1783. doi: 10.1038/onc.2012.205

Figure 7.

Figure 7

CD151 affects β4 distribution and phosphorylation. A, Mouse tumor-derived cell lines were permeabilized and stained for integrin β4. B, Keratinocytes were isolated from wild type and null mice and then cultured for a few weeks before integrin β4 subunit staining. Bar = 5 µm. (A, B) Linear staining intensity, across the diameter of representative cells, was measured using the Image J program (from NIH). C, Human A431 cells, stably ablated for CD151, were treated with TPA (50ng/ml) or EGF (100ng/ml) for 5 min and 1 hr, and then blotted for the indicated proteins, using antibodies for β4-S1424, β4-S1356, and total β4.