Table 2.
Existing reporter lines used to visualize myeloid cells in zebrafish
| Reporter line (ZFIN genotype) | Promoter origin | Cell type labeled | Reference | Notes |
| Tg(spi1:EGFP)pA301 | Spi1/Pu.1 | Myeloid cells | (Ward et al., 2003) | Embryonic stage examined |
| Tg(zpu.1:EGFP)df5 | Spi1/Pu.1 | Myeloid, early lymphatic cells | (Hsu et al., 2004) | Both adult and embryos examined |
| Tg(fli1a:EGFP)y1 | Fli1a | Macrophages, Endothelial cells | (Lawson and Weinstein, 2002; Feng et al., 2010) | Primitive macrophages labeled |
| Tg(mpx:GFP)i113/i114 | Mpx | Neutrophils | (Renshaw et al., 2006) | Lower expression in primitive macrophages |
| Tg(mpx:GFP)uwm1 | Mpx | Neutrophils | (Mathias et al., 2006; Mathias et al., 2009b) | Lower expression in primitive macrophages |
| Tg(lyz:EGFP)nz117 | Lyz/lysC | Neutrophils | (Hall et al., 2007; Feng et al., 2010) | Expression in primitive macrophages |
| Tg(lyz:dsRed)nz50 | Lyz/lysC | Neutrophils | (Hall et al., 2007; Feng et al., 2010) | Expression in primitive macrophages |
| CLGY463(YFP) | Myc enhancer | Neutrophils | (Meijer et al., 2008) | A subset of neutrophils labeled |
| Tg(mpx:mCherry) | Mpx | Neutrophils | (Yoo et al., 2010) | Lower expression in macrophages |
| Tg(mpx:Dendra2) | Mpx | Neutrophils | (Walters et al., 2010; Yoo et al., 2010; Yoo and Huttenlocher, 2011) | Lower expression in macrophages |
| Tg(fms:GAL4.VP16)i186 | Fms (CSF1R) | Macrophages | (Gray et al., 2011) | |
| Tg(mpeg1:mCherry) | Mpeg1 | Macrophages | (Ellett et al., 2011) | Active only in the embryo and larvae |
| Tg(mpeg1:EGFP) | Mpeg1 | Macrophages | (Ellett et al., 2011) | Active only in the embryo and larvae |
| Tg(mpeg1:Gal4-VP16) | Mpeg1 | Macrophages | (Ellett et al., 2011) | Active only in the embryo and larvae |
| Tg(mhc2dab:GFP) | Mhc2dab | B lymphocytes, eosinophils, macrophages and DCs | (Wittamer et al., 2011) | Adult animal |
| Tg (cd45:DsRed) | Cd45 | Myeloid cells and T lymphocytes | (Wittamer et al., 2011) | |
| Tg(mhc2dab:GFP and cd45:DsRed) | Mhc2dab, cd45 | Macrophages and DCs | (Wittamer et al., 2011) |
DCs, dendritic cells.