Table 1.
Relative gene expression pattern in at-risk, new-onset and long-term type 1 diabetes (T1D) patients compared to healthy controls (HT)
| Gene | At-risk (AT) | New-onset (NO) | Long-term (LT) |
|---|---|---|---|
| CD3G | ↑versus HT | ↑versus HT | ↓versus HT |
| S100A10 | ↓versus HT | ||
| S100A13 | ↑versus HT | ↑versus HT | ↓versus HT |
| CD11b | ↑versus HT | ↓versus HT | |
| TLR-9 | ↑versus HT | ↓versus HT | |
| CD20 | ↓versus HT | ||
| S100A6 | ↓versus HT | ||
| S100A11 | ↓versus HT | ||
| CTLA4 | ↓versus HT | ||
| CTLA4/CD3G | ↓versus HT | ↓versus HT | ↑versus HT |
Increase and decrease, in gene expression or gene expression ratio relative to controls. CTLA4: cytotoxic T lymphocyte-associated antigen 4; HT: healthy; TLR: Toll-like receptor.