Fig. 2.

Principal components analysis (PCA) of cytokines between sexes by age. PCA identified growth-regulated oncogene (GRO) (CXCL1), platelet-derived growth factor (PDGF)-AA, sCD40L, interleukin (IL)-8, vascular endothelial growth factor (VEGF) and fibroblast growth factor (FGF)-2 as a set of classifiers discriminating between female and male subjects under 50 years of age (a). PCA identified macrophage-derived chemokine (MDC) (CCL22), sCD40L, PDGF-AA and FGF-2 as a set of classifiers discriminating between female and male subjects aged 50 years and older (b). Females are represented with red dots and males with blue dots.