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. Author manuscript; available in PMC: 2013 Sep 26.
Published in final edited form as: J Am Chem Soc. 2012 Sep 17;134(38):15765–15772. doi: 10.1021/ja303612d

Table 1.

Composition, yield and diameter of NPs in pure water in the absence/presence of IgG (133 nM) in water

NP# Feed ratio of functional monomers
[%]a 		Yield [%] Diameter
[nm]b 		Diameter after
the addition
of IgG [nm]c
TBAm APM AAc
1 40 0 0 61.6 56 Aggregation d
2 0 5 0 30.1 94 89
3 0 0 5 84.1 20 20
4 0 0 0 87.7 88 105
5 40 5 0 26.4 110 110
6 40 0 5 64.0 60 Aggregation d
7 40 0 20 65.2 64 Aggregation d
8 40 0 40 48 58 Aggregation d
a

NIPAm is present according to the following relationship (NIPAm = 98-TBAm + APM + AAc). In all cases, Bis is present as 2% of the total monomer composition.

b

Average of at least 3 independent measurements (standard deviation 0.2 to 1.9 nm)

c

Average of at least 3 independent measurements (standard deviation 0.1 to 2.1 nm)

d

Aggregation is defined by the observation of poly-modality with formation of micron-sized species.