Table 3.
Performance of ICD-9 coding algorithms for a diagnosis of heart failure or cardiomyopathy at any time during the study period when compared to chart-review
| AUTOMATED DATA HEART FAILURE EVENT DEFINITION | |||
|---|---|---|---|
| Algorithm #1 ≥1 primary discharge dx of HF/CM N=43 (weighted N=5) |
Algorithm #2 ≥1 primary discharge OR ≥3 secondary discharge OR ≥2 outpatient OR ≥3 ED OR ≥2 secondary discharge + ≥1 outpatient diagnosis of HF/CM N=124 (weighted N=18) |
Algorithm #3 Any ICD-9 code for HF/CM N=166 (weighted N=40) |
|
| (A) Clinical chart diagnosis of heart failure events N=92 (weighted N=17) |
Sens = 16.6 (5.3–41.4) Spec = 99.5 (97.9–99.9) PPV = 59.3 (19.2–89.9) NPV =96.4 (94.0–97.8) |
Sens = 68.0 (43.6–85.4) Spec = 98.3 (96.3–99.2) PPV = 63.9 (40.6–82.1) NPV = 98.6 (96.7–99.4) |
Sens = 93.0 (67.7–98.8) Spec = 93.7 (90.8–95.8) PPV = 40.0 (26.3–55.8) NPV = 99.7 (98.0–99.9) |
| (B) LVEF <50% N=52 (weighted N=8) |
Sens = 20.6 (4.5–59.0) Spec = 99.2 (97.6–99.7) PPV = 34.1 (7.4–77.2) NPV = 98.4 (96.5–99.3) |
Sens = 55.8 (23.8–83.5) Spec = 96.5 (94.1–97.9) PPV = 24.3 (10.0–48.2) NPV = 99.1 (97.4–99.7) |
Sens = 79.6 (41.2–95.6) Spec = 91.4 (88.2–93.8) PPV = 15.9 (7.5–30.7) NPV = 99.6 (97.9–99.9) |
| (C) Either A or B (gold standard) N=108 (weighted N=21) |
Sens = 14.0 (4.5–36.2) Spec = 99.5 (97.9–99.9) PPV = 59.3 (19.2–89.9) NPV =95.5 (93.0–97.2) |
Sens = 61.5 (39.6–79.5) Spec = 98.5 (96.6–99.3) PPV = 68.6 (44.9–85.4) NPV =97.9 (95.9–99.0) |
Sens = 87.7 (65.6–96.4) Spec = 94.2 (91.3–96.1) PPV = 44.9 (30.5–60.3) NPV = 99.3 (97.6–99.8) |