Table 3.

Multivariate Analysis of Risk Factors for Time to Progression of ALI

Risk Factor	Relative Difference (hours)	95% CI	P Value
Age	1.5	0.2–2.7	.02
Sepsis	−46	−89–−3	.03
Female gender	19	−19–57	.32
Race
Caucasian	0
Asian	−28	−79–23	.28
Black	5	−64–75	.88
Other	−42	−124–39	.30
Alcohol usea	31	−10–73	.14
Blood transfusionsb	−5	−47–38	.82
Chronic diseasec	17	−22–57	.39
Positive cultured	−21	−60–18	.28
Smoker (current)	−33	−83–18	.20
Smoker (former)	−44	−98–10	.11

Abbreviations: ALI, acute lung injury; CI, confidence interval; APACHE II, Acute Physiology And Chronic Health Evaluation II.

^aReported alcohol consumption greater than or equal to 1 drink per day.

^bTransfusion of blood products, including red blood cells, platelets, or fresh frozen plasma, within 72 hours prior to diagnosis of ALI.

^cAs defined in the APACHE II scoring system, the presence of liver cirrhosis, congestive heart failure (New York Heart Association class IV), chronic hemodialysis, or severe immunosuppression.

^dAny positive microbiologic culture from any source taken within 72 hours prior to diagnosis of ALI.